Drugs which are additive with or potentiate the effects of acetylcholine include (a) methacholine (b) scopolamine (c) pralidoxime (d) neostigmine (e) pilocarpine
(a), (d) and (e)
(b), (d), and (e)
(c), (d) and (e)
(a), (b), and (c)
(a), (c), and (d)
1 explanations
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drugs which potentiate cholinergic stimulation can do so by being either direct acting cholinergic agonists, acting on the cholinergic receptor, or by indirectly increasing the duration of action Ach by preventing its enzymatic degradation. Methacholine and pilocarpine are direct-acting cholinergic agonists, whereas neostigmine acts indirectly. Scopolamine is a muscarinic antagonist like atropine, and will reduce or block cholinergic action via direct receptor antagonism. Pralidoxime is a chemical antidote used to regenerate AchE after nerve gas or insecticide exposure.
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