Which of the following are important criteria for the adequate clinical evaluation of a new drug?
a. comparison with a placebo
b. evaluation of side effects
c. utilization of control groups
d. comparison with a standard drug
e. double blind experimental design

all of the above

b, d and e only

b, c, and e

a, c, d, and e

a, b, d, and e

a, b, c, and d