A 55 year old patient had a squamous cell carcinoma of the oral cavity 5 years previously. His medical management involved surgery, chemotherapy and intensity-modulated radiotherapy (IMRT) of 65 Gy which included the mandible. The most appropriate management for the extraction of tooth 3.7 under local anesthesia is

hyperbaric oxygen treatment prior to and following tooth extraction.

using local anesthetic without epinephrine.

hyperbaric oxygen treatment prior to tooth extraction.

transfusion with packed red blood cells.