Violation

When comparing ibuprofen and celecoxib used in therapeutic doses, which of the following statements is true?

Ibuprofen inhibits both COX-1 and COX-2, celecoxib inhibits mostly COX-2.

Ibuprofen inhibits mostly COX-1, celecoxib inhibits mostly COX-2

Ibuprofen inhibits mostly COX-1, celecoxib inhibits both COX-1 and COX-2.

Both ibuprofen and celecoxib are potent inhibitors of COX-1 and COX-2.

Please describe the matter of abuse