Shortly after the administration of an inferior alveolar nerve block, a healthy adult patient rapidly develops a facial rash. Which of the following signs and symptoms should be watched for before initiating the planned dental treatment?
1. Pallor and perspiration.
2. Shortness of breath.
3. Hyperventilation.
4. Edema of the lips.

(2) and (4)

(1) (2) (3)

(1) and (3)

(4) only

All of the above.