The current recommended regimen of antibiotic prophylaxis for a patient with a prosthetic heart valve and an allergy to penicillin is
clindamycin 600mg orally one hour before procedure only.
amoxicillin 3g orally one hour before procedure; then 1.5g six hours after initial dose.
amoxicillin 2g orally one hour before procedure only.
clindamycin 300mg orally one hour before procedure; then 150mg six hours after initial dose.
erythromycin stearate, 2g orally two hours before procedure only.
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