The most widely used tricyclic antidepressant (TCA) drug is:

  • Correct answer

    Amitriptyline (Elavil)

  • Imipramine (Tofranil)

  • Desipramine (Norpramin)

  • Nortriptyline (Pamelor)

  • Doxepin (Sinequan)

This question is one of 43 in Antidepressants and Antihistamines. Test yourself on all of them.

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Explanations

  • The tricyclic antidepressants are generally considered to be the drugs of first choice for the treatment ofunipolar disorder (depresslor). These drugs inhitlit the neuronal re-up- take of norepinephrine and s€rotonin (5-HT) in the brain. This results in the potentia- tion oftheir neurotransmitter actions at postsynaptic receptors.

    — oneguy +1 helpful

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