The cause of death from acute barbiturate poisoning or overdosage is

respiratory failure

angina pectoris

CNS depression

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Contraindications to the use of ultra-short-acting barbiturates for general anesthesia: 1. Porphyria 2. Liver dysfunction (they are metabolized in the liver) 3. Emphysema 4. Previous addiction to sedative hypnotic drugs

All of the above

1,2,3

1 and 3

2 and 4

4 only

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All of the following statements concerning barbiturates are true EXCEPT one. Which one is the exception?

Barbiturates may increase the half-lives of drugs metabolized by the liver

Barbiturates depress neuronal activily by increasing membrane ion conductance (primarily chloride), reducing glutamate-induced depolarizations and potentiating the inhibitory effects of GABA

Compared with benzodiazepines, the barbiturates exhibit a steeper dose-response relationship

Barbiturates may precipitate acute porphyria in susceptible patients

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All the following are classified as antiepileptics EXCEPT one. Which one is the.EXCEPIlON?

Propafenone (Rythmol)

Gabapentin (Neurontin)

Carbamazepine (Tegretol)

Phenytoin (Dilantin)

Phenobarbital (Luminal)

Diazepam (Valium)

Vaplroic acid (Depakene)

Ethosuximide (Zarontin)

Primidone (Mysoline)

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Grand mal seizure is

Tonic-clonic generalized seizure

Absence generalized seizure

Myoclonic generalized seizure

Partial seizure

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