Barbiturates are metabolized in

The length of action can be related to the lipid solubility of barbiturates with the ultrashort being the ___1___ lipid soluble and the long acting having the ___2___ lipid solubility.

Barbiturates do NOT possess serious drug dependence potential.

The length of hypnotic action of ultrashort-acting barbiturate after a single dose is

The length of hypnotic action of Intermediate-acting barbiturate after a single dose is

The length of hypnotic action of long-acting barbiturate after a single dose is

Ultrashort-acting barbiturates

Short-acting barbiturates

Intermediate-acting barbiturates

Long-acting barbiturates

Thiopental (Pentothal)

Methohexital (Brevital)

Secobarbital (Seconal)

Pentobarbital (Nembutal)

Amobarbital (Amytal)

Butabarbital (Butisol)

Phenobarbital (Luminal)

Mephobarbital (Mebaral)

Primidone (Mysoline)

Barbiturates do not possess analgesic properties

The cause of death from acute barbiturate poisoning or overdosage is

Contraindications to the use of ultra-short-acting barbiturates for general anesthesia: 1. Porphyria 2. Liver dysfunction (they are metabolized in the liver) 3. Emphysema 4. Previous addiction to sedative hypnotic drugs

All of the following statements concerning barbiturates are true EXCEPT one. Which one is the exception?

All the following are classified as antiepileptics EXCEPT one. Which one is the.EXCEPIlON?

Grand mal seizure is

What is used for status epilepticus and in emergency treatment of seizures?

Phenytoin (Dilantin) is ___?___ antiepileptic drug.

Phenytoin (Dilantin)

___?___-induced gingival hyperplasia is common and may partially or totally obscure the crowns of teeth.

Valproic acid (Depakene) is ___?___ antiepileptic drug.

Gabapentin (Neurontin) is ___?___ antiepileptic drug.

Divalproex (Depakote) is ___?___ antiepileptic drug.

Felbamate (Felbatol) is ___?___ antiepileptic drug.

Lamotrigine (Lamictal) is ___?___ antiepileptic drug.

Pregabalin (Lyrica) is ___?___ antiepileptic drug.

Tiagabine (Gabitril) is ___?___ antiepileptic drug.

Topiramate (Topamax) is ___?___ antiepileptic drug.

Ethosuximide (Zarontin) is ___?___ antiepileptic drug. Used in the treatment of absence seizures.

Phenobarbital (Luminal) is ___?___ antiepileptic drug.

Diazepam (Valium) is ___?___ antiepileptic drug.

Clonazepam (Klonopin) is ___?___ antiepileptic drug.

Lorazepam (Ativan) is ___?___ antiepileptic drug.

The most widely used tricyclic antidepressant (TCA) drug is:

Which drug is the current drug of cholce for the treatment ofthe manic phase of bipolar disorder (or manic-depressive syndrome)?

___?___ displays the greatest anticholinergics effects (especially xerostomia), desipramine the least.

Anticholinergic adverse side effects include: 1. dry mouth 2. constipation 3. blurred vision 4. tachycardia.

Monoamine Oxidase (MAO) inhibltors are often used as third-line agents in cases of refractory and atypical depression. Whlch Two drugs below are MAO inhlbitors? 1. Doxepin (Sinequan) 2. Tranylcypromine (Parnate) 3. Imipramine (Tofranil) 4. Phenelzine (Nardil)

The vasoconstrictor epinephrine in local anesthetic injections must be used cautiously in patients taking all ofthe following antidepressant drugs EXCEPT one in order to avoid transient and significant increases in blood pressure. Which one is the EXCEPTION

Local anesthetics containing epinephrine are genemlly contraindicated in patients who are taking

Which two groups of antidepressant drugs has the highest incidence of dry mouth (xerostomia)? 1. Tricyclic antidepressants (i.e. Elavil) 2. Selective serotonin reuptake inhibitors (i.e., Prozac and Paxil) 3. Serotonin and norepinephrine reuptake inhibitors (i.e., Effexor and Cymbalta) 4. Monoamine oxidase inhibitors (i.e., Nardil)