A patient with a prosthetic heart valve requires a tooth extraction and reports anaphylaxis to penicillin. According to the 2021 American Heart Association scientific statement, which oral antibiotic is an appropriate choice for prophylaxis?

  • Correct answer

    Azithromycin

  • Clindamycin

  • Cephalexin

  • Amoxicillin

This question is one of 15 in AFK practice: Pharmacology, local anesthesia and emergencies. Test yourself on all of them.

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Explanations

  • The 2021 AHA statement lists azithromycin, clarithromycin or doxycycline for penicillin-allergic patients. Clindamycin is no longer recommended because of more frequent and severe adverse reactions, and cephalosporins should be avoided after penicillin anaphylaxis.

    Source: Wilson et al., Prevention of Viridans Group Streptococcal Infective Endocarditis, AHA 2021 link — oneguy

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