A healthy 60 kg adult is to receive 4% articaine with 1:100,000 epinephrine. Using the Canadian product monograph maximum of 7 mg/kg (not to exceed 500 mg), what is this patient's maximum recommended dose of articaine?

  • Correct answer

    420 mg

  • 500 mg

  • 264 mg

  • 300 mg

This question is one of 15 in AFK practice: Pharmacology, local anesthesia and emergencies. Test yourself on all of them.

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Explanations

  • 7 mg/kg x 60 kg = 420 mg, which is below the 500 mg absolute ceiling. The 500 mg ceiling only becomes the limiting value in patients heavier than about 71 kg.

    Source: 4% Astracaine Dental with Epinephrine product monograph (Health Canada) link — oneguy

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